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In vivo anti-leishmanial activity of particles containing AMB, DETA/NO, or both drugs, compared to Ambisome® and  Fungizone®.

Journal: International Journal for Parasitology: Drugs and Drug Resistance

Article Title: Supplementation of host response by targeting nitric oxide to the macrophage cytosol is efficacious in the hamster model of visceral leishmaniasis and adds to efficacy of amphotericin B

doi: 10.1016/j.ijpddr.2016.01.001

Figure Lengend Snippet: In vivo anti-leishmanial activity of particles containing AMB, DETA/NO, or both drugs, compared to Ambisome® and Fungizone®.

Article Snippet: Significant differences (P < 0.05) were observed in activities of other particles and the commercial formulation, having leishmanicidal activity in the rank-order 2-drug particles > Ambisome®>AMB particles > Fungizone®.

Techniques: In Vivo, Activity Assay